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Job-Art: Wissenschaftliche Jobausschreibungen

Master Thesis for 1 year with "geringfügige Anstellung"

Molecular biology, ovarian cancer
Medizinische Universität Wien, AKH


Master Thesis - Molecular Biology of Ovarian Cancer


Fachgebiet: Molecular Biology

Ort/Forschungsstätte: Medical University of Vienna (AKH)

Dept. of Gynecology and Obstetrics

Translational Gynaecology

Email: dan.cacsire-castillo(at)meduniwien.ac.at

Kontaktperson: Dan Cacsire Castillo-Tong (0043-1-40400-78330)

Webadresse: www.octips.eu;




Epithelial ovarian cancer has a worldwide annual incidence and mortality of 24000 and 150000, respectively. Standard treatment includes debulking surgery and platinum-based chemotherapy. Although most patients show primary response, they frequently relapse and die of disease progression. The 5-year survival rate is below 40%. Molecular analyses of tumor tissues and patient-derived cell lines indicate that loss of the cell cycle control due to loss of wild-type TP53 is the major cause of tumorigenesis and disease progression. In addition, tumor cells express specific antigens, which are usually not expressed in epithelial cells.

Objectives: to compare expression profiles of different types of ovarian cancers; to molecularly analyze tumor specific antigen; to define tumor specific therapeutic targets; to test therapeutic strategies

Duration: 1 year, start as soon as possible

Allowrance: Geringfügige Anstellung

Qualification requirements: Bachelor’s degree in molecular biology or relevant fields; having completed all theoretical courses at FH or universities (HauptUni, BOKU); wetlab experiences; interest and enthusiasms in science; strong analytical and organizational skills; open-minded; very good English and German skill is a must.


Name: Dan Cacsire Castillo-Tong
Telefon: 069917083221

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